First, PPI use was defined as a binary variable (no PPI use versus PPI use). In addition, participants were asked whether they use over the counter medication. Actual PPI use, type of PPI and dosage of PPIs in the week prior to the study visit was verified with the participants at the study visit, and adapted according to patient reporting in case of discrepancy. PPI use, type of PPI and dosage of PPIs were retrieved from the electronic patient file in the week before the study visit. In our center and in many other transplant centers, PPIs are routinely prescribed after kidney transplantation for exertion of their gastro-protective properties, and, until recently, they were considered harmless, without an incentive for stopping. 40th Anniversary Special Collection: Kidney Transplantation.40th Anniversary Special Collection: CKD.
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